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Sigma-1 receptor antagonist 1
CAS No. 1639220-19-1
Sigma-1 receptor antagonist 1( —— )
Catalog No. M26443 CAS No. 1639220-19-1
Sigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 222 | Get Quote |
|
| 10MG | 357 | Get Quote |
|
| 25MG | 597 | Get Quote |
|
| 50MG | 851 | Get Quote |
|
| 100MG | 1152 | Get Quote |
|
| 500MG | 2313 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSigma-1 receptor antagonist 1
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NoteResearch use only, not for human use.
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Brief DescriptionSigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor.
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DescriptionSigma-1 receptor antagonist 1 is an effective and selective antagonist of sigma-1 receptor. Sigma-1 receptor antagonist 1 exhibits antineuropathic pain activity and can be used in the treatment of neuropathic pain studies.(In Vitro):Sigma?1 receptor antagonist 1 exhibits a high binding affinity to σ1R receptor with Ki of 1.06 nM and good σ-1/2 selectivity (1344-fold).(In Vivo):In mice formalin model and rats CCI models of neuropathic pain, Sigma?1 receptor antagonist 1 exerts dose-dependent antinociceptive effects.
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In VitroSigma?1 receptor antagonist 1 exhibits a high binding affinity to σ1R receptor (Ki = 1.06 nM) and good σ-1/2 selectivity (1344-fold).
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In VivoSigma1 receptor antagonist 1 exerts dose-dependent antinociceptive effects in mice formalin model and rats CCI models of neuropathic pain.
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Synonyms——
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PathwayAutophagy
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TargetSigma receptor
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RecptorTLR7| TLR8
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Research Area——
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Indication——
Chemical Information
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CAS Number1639220-19-1
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Formula Weight380.31
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Molecular FormulaC19H23Cl2N3O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 6.25 mg/mL (16.43 mM)
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SMILESCc1nc(nc(OCCCN2CCCCC2)c1Cl)-c1ccc(Cl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Martha A. MILLER, et al. Vaccine compositions and methods of use to treat neonatal subjects.
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